anti- PACSIN2 antibody

PRODUCT INFORMATION

Product Name

PACSIN2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

IMMUNOGEN INFORMATION

Immunogen

protein kinase C and casein kinase substrate in neurons 2

Observed MW

60-65 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UNF0

IP Result of anti-PACSIN2 (IP:FNab06101, 4ug; Detection:FNab06101 1:500) with NIH/3T3 cells lysate 1200ug.

NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab06101(PACSIN2 Antibody) at dilution of 1:600