anti- PAPD5 antibody

PRODUCT INFORMATION

Product Name

PAPD5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

IMMUNOGEN INFORMATION

Immunogen

PAP associated domain containing 5

Synonyms

PAPD5, Terminal uridylyltransferase 3, TRF4 2, TUTase 3

Observed MW

50 kDa, 80 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

Q8NDF8

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab06139(PAPD5 antibody) at dilution of 1:1000