anti- PARD6B antibody

PRODUCT INFORMATION

Product Name

PARD6B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

IMMUNOGEN INFORMATION

Immunogen

par-6 partitioning defective 6 homolog beta(C. elegans)

Synonyms

PAR6B

Observed MW

50-53 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP, FC

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9BYG5

IP Result of anti-PARD6B (IP:FNab06147, 3ug; Detection:FNab06147 1:200) with HEK-293 cells lysate 6000ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab06147(PARD6B antibody) at dilution of 1:500