anti- PDCD4 antibody

PRODUCT INFORMATION

Product Name

PDCD4 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).

IMMUNOGEN INFORMATION

Immunogen

programmed cell death 4(neoplastic transformation inhibitor)

Synonyms

H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a

Observed MW

56 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:1000-1:4000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q53EL6

HeLa cells were subjected to SDS PAGE followed by western blot with FNab06240(PDCD4 Antibody) at dilution of 1:2000