anti- PER2 antibody

PRODUCT INFORMATION

Product Name

PER2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.

IMMUNOGEN INFORMATION

Immunogen

period homolog 2

Synonyms

FASPS, hPER2, KIAA0347, PER2, period homolog 2

Observed MW

136 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

O15055

IMAGES

BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab06312(PER2 antibody) at dilution of 1:600