anti- PFKFB3-Specific antibody

PRODUCT INFORMATION

Product Name

PFKFB3-Specific antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.

IMMUNOGEN INFORMATION

Immunogen

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Synonyms

6PF 2 K/Fru 2,6 P2ase 3, FLJ37326, IPFK2, PFK/FBPase 3, PFK2, PFKFB3

Observed MW

58 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q16875

mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab06339(PFKFB3-Specific antibody) at dilution of 1:600