anti- PHOX2B antibody

PRODUCT INFORMATION

Product Name

PHOX2B antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

IMMUNOGEN INFORMATION

Immunogen

paired-like homeobox 2b

Synonyms

NBPhox, Neuroblastoma Phox, paired like homeobox 2b, PHOX2B, PHOX2B homeodomain protein, PMX2B

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:1000-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q99453

Neuro-2a cells were subjected to SDS PAGE followed by western blot with FNab06409(PHOX2B Antibody) at dilution of 1:2500