anti- PLEKHF1 antibody

anti- PLEKHF1 antibody

Product Name

PLEKHF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.

IMMUNOGEN INFORMATION

Immunogen

pleckstrin homology domain containing, family F(with FYVE domain) member 1

Synonyms

Apoptosis inducing protein, APPD, LAPF, Phafin 1, PHAFIN1, PLEKHF1, ZFYVE15

Observed MW

31 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q96S99

human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06540(PLEKHF1 antibody) at dilution of 1:500