anti- Podocalyxin antibody

Product Name

Podocalyxin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Podocalyxin, also known as podocalyxin-like protein 1(PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.

IMMUNOGEN INFORMATION

Immunogen

podocalyxin

Synonyms

GCTM-2 antigen,Gp200,Podocalyxin-like protein 1,PC,PCLP-1,PODXL,PCLP, PCLP1

Observed MW

59 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, FC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O00592

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06597(PODXL antibody) at dilution of 1:500