anti- POLR2C antibody

Product Name

POLR2C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft(By similarity).

IMMUNOGEN INFORMATION

Immunogen

polymerase(RNA) II(DNA directed) polypeptide C, 33kDa

Observed MW

33 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P19387

IP Result of anti-POLR2C (IP:FNab06621, 4ug; Detection:FNab06621 1:500) with HeLa cells lysate 2000ug.

human kidney tissue were subjected to SDS PAGE followed by western blot with FNab06621(POLR2C antibody) at dilution of 1:500