anti- PPP2R2B antibody

Product Name

PPP2R2B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).

IMMUNOGEN INFORMATION

Immunogen

protein phosphatase 2(formerly 2A), regulatory subunit B, beta isoform

Synonyms

PP2A subunit B isoform beta, PP2A subunit B isoform R2 beta, PP2AB BETA, PP2APR55 BETA, PPP2R2B, PR2AB BETA, PR2AB55 BETA, PR2APR55 BETA, PR52B, PR55 BETA, SCA12

Observed MW

52 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IP

Recommended Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q00005

IP Result of PPP2R2B antibody (IP: FNab06717, 4ug; Detection: FNab06717 1:500) with SH-SY5Y cells lysate 2000ug.

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06717(PPP2R2B antibody) at dilution of 1:500