anti- RANBP10 antibody

anti- RANBP10 antibody

Product Name

RANBP10 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as a guanine nucleotide exchange factor(GEF) for RAN GTPase(By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function(By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway.

IMMUNOGEN INFORMATION

Immunogen

RAN binding protein 10

Synonyms

KIAA1464

Observed MW

67-70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q6VN20

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