anti- RCC1 antibody

anti- RCC1 antibody

Product Name

RCC1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.

IMMUNOGEN INFORMATION

Immunogen

regulator of chromosome condensation 1

Synonyms

Cell cycle regulatory protein, CHC1, RCC1, RCC1 I

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF

Recommended Dilution

WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P18754

IMAGES

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07208(SNHG3-RCC1 antibody) at dilution of 1:100

IP Result of anti-RCC1 (IP:FNab07208, 3ug; Detection:FNab07208 1:1000) with HEK-293 cells lysate 1000ug.

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07208(SNHG3-RCC1 antibody) at dilution of 1:300