anti- RCC1 antibody

anti- RCC1 antibody

Product Name

RCC1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex(together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

IMMUNOGEN INFORMATION

Immunogen

regulator of chromosome condensation 1

Synonyms

CHC1

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P18754

IMAGES

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07209(SNHG3-RCC1 antibody) at dilution of 1:100

IP Result of anti-RCC1 (IP:FNab07209, 3ug; Detection:FNab07209 1:1500) with HeLa cells lysate 3000ug.

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07209(SNHG3-RCC1 antibody) at dilution of 1:300