anti- RGS10 antibody

anti- RGS10 antibody

Product Name

RGS10 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling(PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein(PubMed:9353196).

IMMUNOGEN INFORMATION

Immunogen

regulator of G-protein signaling 10

Observed MW

20-22 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O43665

IMAGES

mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab07264(RGS10 antibody) at dilution of 1:600