anti- RGS2 antibody

anti- RGS2 antibody

Product Name

RGS2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).

IMMUNOGEN INFORMATION

Immunogen

regulator of G-protein signaling 2, 24kDa

Synonyms

G0S8, RGS2

Observed MW

24kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P41220

IMAGES

Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07269(RGS2 antibody) at dilution of 1:50

fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab07269(RGS2 Antibody) at dilution of 1:500