anti- RMI1 antibody

anti- RMI1 antibody

Product Name

RMI1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions(DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

IMMUNOGEN INFORMATION

Immunogen

RMI1, RecQ mediated genome instability 1, homolog

Synonyms

C9orf76

Observed MW

75 kDa

APPLICATION

Tested Application

ELISA, IHC, IP, WB

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9H9A7

IMAGES

Immunohistochemistry of paraffin-embedded human gliomas using FNab07321(RMI1 antibody) at dilution of 1:100

IP Result of anti-RMI1 (IP:FNab07321, 3ug; Detection:FNab07321 1:1500) with HeLa cells lysate 3800ug.

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07321(RMI1 antibody) at dilution of 1:500