anti- RNase T2 antibody

anti- RNase T2 antibody

Product Name

RNase T2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

RNASET2(Ribonuclease T2) is also named as RNASE6PL(Ribonuclease 6) and belongs to the RNase T2 family. It is a unique member of the growing family of tumor-antagonizing genes and behaves as a class II tumor suppressor and abolish the tumorigenic potential of an ovarian cancer-derived cell line. This protein has 2 isoforms produced by alternative splicing. Both mildly glycosylated (ranging from38 to 45 kDa) and highly glycosylated forms (ranging from 50 to 80 kDa) of human tumor suppressor protein RNASET2 can be detected in immunoblotting

IMMUNOGEN INFORMATION

Immunogen

ribonuclease T2

Synonyms

Ribonuclease 6, Ribonuclease T2, RNASE6PL, RNASET2

Observed MW

29 kDa

APPLICATION

Tested Application

ELISA, IHC, IF, WB, IP

Recommended Dilution

WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O00584

IMAGES

Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07324(RNASET2 antibody) at dilution of 1:100

IP Result of anti-RNase T2 (IP:FNab07324, 4ug; Detection:FNab07324 1:300) with BxPC-3 cells lysate 4000ug.

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07324(RNASET2 antibody) at dilution of 1:500