anti- RNASEH1 antibody

anti- RNASEH1 antibody

Product Name

RNASEH1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids(PubMed:10497183). Plays a role in RNA polymerase II(RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II(PubMed:21700224).

IMMUNOGEN INFORMATION

Immunogen

ribonuclease H1

Synonyms

RNH1

Observed MW

32 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

O60930

IMAGES

IP Result of anti-RNASEH1 (IP:FNab07327, 3ug; Detection:FNab07327 1:500) with HeLa cells lysate 1200ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07327(RNASEH1 antibody) at dilution of 1:500