anti- RRAGB antibody

anti- RRAGB antibody

Product Name

RRAGB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.

IMMUNOGEN INFORMATION

Immunogen

Ras-related GTP binding B

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q5VZM2

IMAGES

Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab07488(RRAGB Antibody) at dilution of 1:50

human testis tissue were subjected to SDS PAGE followed by western blot with FNab07488(RRAGB antibody) at dilution of 1:500