anti- SAE1 antibody

anti- SAE1 antibody

Product Name

SAE1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

IMMUNOGEN INFORMATION

Immunogen

SUMO1 activating enzyme subunit 1

Synonyms

AOS1, SUA1, UBLE1A

Observed MW

38 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UBE0

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab07577(SAE1 Antibody) at dilution of 1:200

A431 cells were subjected to SDS PAGE followed by western blot with FNab07577(SAE1 antibody) at dilution of 1:300