anti- SCD antibody

anti- SCD antibody

Product Name

SCD antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates(PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids(PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation(By similarity). Plays an important role in body energy homeostasis(By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides(By similarity).

IMMUNOGEN INFORMATION

Immunogen

stearoyl-CoA desaturase(delta-9-desaturase)

Synonyms

Acyl CoA desaturase, Delta(9) desaturase, FADS5, Fatty acid desaturase, MSTP008, SCD, SCD1, SCDOS, Stearoyl CoA desaturase

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O00767

IMAGES

Immunohistochemistry of paraffin-embedded human liver using FNab07627(SCD antibody) at dilution of 1:200

rat liver were subjected to SDS PAGE followed by western blot with FNab07627( SCD Antibody) at dilution of 1:1000