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FNab07766

anti- SETD1B antibody

anti- SETD1B antibody

$310.00 USD
$310.00 USD
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size

anti- SETD1B antibody

Product Name

SETD1B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.

IMMUNOGEN INFORMATION

Immunogen

SET domain containing 1B

Synonyms

KIAA1076, KMT2G, SET1B

Observed MW

260 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IHC,IF

Recommended Dilution

WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q9UPS6

IMAGES

 

Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab07766(SETD1B Antibody) at dilution of 1:50
Immunofluorescent analysis of ( 4% PFA) fixed MCF-7 cells using FNab07766 (SETD1B antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
IP Result of anti-SETD1B (IP:FNab07766, 5ug; Detection:FNab07766 1:300) with MCF-7 cells lysate 3250ug.
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07766(SETD1B antibody) at dilution of 1:1000

 

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