anti- SHMT1 antibody

anti- SHMT1 antibody

Product Name

SHMT1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

serine hydroxymethyltransferase 1 (soluble)

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P34896

IMAGES

Immunohistochemistry of paraffin-embedded rat kidney using FNab07850( SHMT1 Antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07850(SHMT1 antibody) at dilution of 1:1000