anti- SIKE1 antibody

anti- SIKE1 antibody

Product Name

SIKE1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements(ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.

IMMUNOGEN INFORMATION

Immunogen

suppressor of IKK epsilon

Synonyms

SIKE

Observed MW

24 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9BRV8

IMAGES

Immunohistochemistry of paraffin-embedded human liver using FNab07867(SIKE1 antibody) at dilution of 1:50

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07867(SIKE1 antibody) at dilution of 1:500