anti- SIRT3 antibody

anti- SIRT3 antibody

Product Name

SIRT3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

IMMUNOGEN INFORMATION

Immunogen

sirtuin (silent mating type information regulation 2 homolog) 3

Synonyms

hSIRT3, SIR2 like protein 3, SIR2L3, SIRT3

Observed MW

44 kDa, 27 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q9NTG7

IMAGES

Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab07881( SIRT3 Antibody) at dilution of 1:100

SW620 cells were subjected to SDS PAGE followed by western blot with FNab07881(SIRT3 antibody) at dilution of 1:1000