anti- SMAD3 antibody

anti- SMAD3 antibody

Product Name

SMAD3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

IMMUNOGEN INFORMATION

Immunogen

SMAD family member 3

Synonyms

MADH3, hMAD 3, hSMAD3, HSPC193, HsT17436, JV15 2, MAD homolog 3, Mad3, Mothers against DPP homolog 3, SMAD 3, SMAD family member 3, SMAD3

Observed MW

48 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P84022

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab07994( SMAD3 Antibody) at dilution of 1:50

Immunofluorescent analysis of HeLa cells using FNab07994 ( SMAD3 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07994( SMAD3 Antibody) at dilution of 1:1000