anti- SMARCE1 antibody

anti- SMARCE1 antibody

Product Name

SMARCE1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

IMMUNOGEN INFORMATION

Immunogen

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

Synonyms

BAF57

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q969G3

IMAGES

Immunohistochemistry of paraffin-embedded human gastric cancer using FNab08014(SMARCE1 antibody) at dilution of 1:100

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08014(SMARCE1 antibody) at dilution of 1:1000