anti- SMURF1 antibody

anti- SMURF1 antibody

Product Name

SMURF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes(PubMed:23999003).

IMMUNOGEN INFORMATION

Immunogen

SMAD specific E3 ubiquitin protein ligase 1

Synonyms

KIAA1625

Observed MW

83-90 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9HCE7

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab08046(SMURF1 Antibody) at dilution of 1:50

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08046(SMURF1 antibody) at dilution of 1:800