anti- SOX7 antibody

anti- SOX7 antibody

Product Name

SOX7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors(By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification(By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter(By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.

IMMUNOGEN INFORMATION

Immunogen

SRY(sex determining region Y)-box 7

Observed MW

42-45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9BT81

IMAGES

Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab08129(SOX7 Antibody) at dilution of 1:50

COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08129(SOX7 Antibody) at dilution of 1:600