anti- SREBF1 antibody

anti- SREBF1 antibody

Product Name

SREBF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway(By similarity). Binds to the sterol regulatory element 1(SRE-1)(5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif(5'-ATCACGTGA-3') and to SRE-1(5'-ATCACCCCAC-3').

IMMUNOGEN INFORMATION

Immunogen

sterol regulatory element binding transcription factor 1

Synonyms

BHLHD1, SREBP1

Observed MW

125 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P36956

IMAGES

IP Result of anti-SREBF1 (IP:FNab08220, 4ug; Detection:FNab08220 1:600) with L02 cells lysate 1500ug.

MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab08220(SREBF1 antibody) at dilution of 1:1000