anti- SRRM1 antibody

anti- SRRM1 antibody

Product Name

SRRM1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer(ESE)-dependent splicing activation by bridging together sequence-specific(SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP(SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.

IMMUNOGEN INFORMATION

Immunogen

serine/arginine repetitive matrix 1

Synonyms

SRM160

Observed MW

120-160 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q8IYB3

IMAGES

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab08242(SRRM1 antibody) at dilution of 1:500