anti- STAM antibody

anti- STAM antibody

Product Name

STAM antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

IMMUNOGEN INFORMATION

Immunogen

signal transducing adaptor molecule(SH3 domain and ITAM motif) 1

Synonyms

STAM1

Observed MW

70 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q92783

IMAGES

IP Result of anti-STAM (IP:FNab08283, 4ug; Detection:FNab08283 1:300) with PC-3 cells lysate 1440ug.

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08283(STAM antibody) at dilution of 1:1500