anti- STK4 antibody

anti- STK4 antibody

Product Name

STK4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

IMMUNOGEN INFORMATION

Immunogen

serine/threonine kinase 4

Synonyms

DKFZp686A2068, KRS2, MST 1, MST1, serine/threonine kinase 4, STE20 like kinase MST1, STK4, YSK3

Observed MW

56 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50

UNIPROT INFORMATION

UniProt ID

Q13043

IMAGES

Immunohistochemistry of paraffin-embedded human prostate cancer using FNab08339(STK4 antibody) at dilution of 1:50

IP Result of anti-STK4/MST1 (IP:FNab08339, 4ug; Detection:FNab08339 1:1000) with HeLa cells lysate 1200ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08339(STK4 antibody) at dilution of 1:1000