anti- SUMO2/3 antibody

anti- SUMO2/3 antibody

Product Name

SUMO2/3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

IMMUNOGEN INFORMATION

Immunogen

SMT3 suppressor of mif two 3 homolog 2

Synonyms

HSMT3, SMT3B, SMT3H2, SUMO3, Smt3A

Observed MW

11 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P61956

IMAGES

Immunohistochemistry of paraffin-embedded human gliomas using FNab08391(SUMO2/3 antibody) at dilution of 1:50

Immunofluorescent analysis of HEK-293 cells using FNab08391 (SUMO2/3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)

Apoptosised HeLa cells were subjected to SDS PAGE followed by western blot with FNab08391(SUMO2/3 antibody) at dilution of 1:100