anti- SUPV3L1 antibody

anti- SUPV3L1 antibody

Product Name

SUPV3L1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome(mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded(ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.

IMMUNOGEN INFORMATION

Immunogen

suppressor of var1, 3-like 1

Synonyms

SUV3

Observed MW

70-80 kDa

APPLICATION

Tested Application

ELISA, IP, WB

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

Q8IYB8

IMAGES

IP Result of anti-SUPV3L1 (IP:FNab08397, 4ug; Detection:FNab08397 1:300) with HeLa cells lysate 1200ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08397(SUPV3L1 Antibody) at dilution of 1:60