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Immunohistochemistry of paraffin-embedded human skeletal muscle using FNab08440(SYNM antibody) at dilution of 1:50 -
Immunofluorescent analysis of HeLa cells using FNab08440 (SYNM antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG -
Y79 cells were subjected to SDS PAGE followed by western blot with FNab08440(SYNM antibody) at dilution of 1:1000
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SKU:FNab08440
anti- SYNM antibody
anti- SYNM antibody
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anti- SYNM antibody
Product Name
SYNM antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Type-VI intermediate filament(IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
IMMUNOGEN INFORMATION
Immunogen
synemin, intermediate filament protein
Synonyms
DMN, KIAA0353, SYN
Observed MW
175 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IF
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
UNIPROT INFORMATION
UniProt ID
IMAGES
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