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Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab08496( TALPID3 antibody) at dilution of 1:200
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SKU:FNab08496
anti- TALPID3 antibody
anti- TALPID3 antibody
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anti- TALPID3 antibody
Product Name
TALPID3 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).
IMMUNOGEN INFORMATION
Immunogen
KIAA0586
APPLICATION
Tested Application
ELISA, IHC
Recommended Dilution
IHC: 1:50-1:500
UNIPROT INFORMATION
UniProt ID
IMAGES
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