anti- TFEC antibody

anti- TFEC antibody

Product Name

TFEC antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F(that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase(TRAP) E-box containing promoter(By similarity). Collaborates with MITF in target gene activation(By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence(By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer(By similarity). Binds DNA in a homo-or heterodimeric form.

IMMUNOGEN INFORMATION

Immunogen

transcription factor EC

Synonyms

BHLHE34, TCFEC, TFECL

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14948

IMAGES