anti- TNFAIP1 antibody

anti- TNFAIP1 antibody

Product Name

TNFAIP1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

IMMUNOGEN INFORMATION

Immunogen

tumor necrosis factor, alpha-induced protein 1(endothelial)

Synonyms

BACURD2, EDP1

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:1000-1:6000; IHC: 1:50-1:600

UNIPROT INFORMATION

UniProt ID

Q13829

IMAGES