anti- TNFR1 antibody

anti- TNFR1 antibody

Product Name

TNFR1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases(aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

IMMUNOGEN INFORMATION

Immunogen

tumor necrosis factor receptor superfamily, member 1A

Synonyms

CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB,IHC, FC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P19438

IMAGES