1 1

FineTest

FNab08854

anti- TOLLIP antibody

anti- TOLLIP antibody

$310.00 USD
$310.00 USD
Sale Sold out
Shipping calculated at checkout.
size

anti- TOLLIP antibody

Product Name

TOLLIP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity(PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates(PubMed:25042851).

IMMUNOGEN INFORMATION

Immunogen

toll interacting protein

Synonyms

IL 1RAcPIP, toll interacting protein, TOLLIP

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:20-1:100

UNIPROT INFORMATION

UniProt ID

Q9H0E2

IMAGES

 

Immunohistochemistry of paraffin-embedded human gliomas using FNab08854(TOLLIP antibody) at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using FNab08854 (TOLLIP antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab08854(TOLLIP antibody) at dilution of 1:500

 

View full details