anti- TOP1 antibody

anti- TOP1 antibody

Product Name

TOP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

IMMUNOGEN INFORMATION

Immunogen

topoisomerase (DNA) I

Synonyms

DNA topoisomerase 1, DNA topoisomerase I, TOP1, TOPI, Top-I, topoisomerase (DNA) I

Observed MW

100 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P11387

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