anti- Transferrin antibody

anti- Transferrin antibody

Product Name

Transferrin antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Serotransferrin(TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin(found both intracellular and in secretions, including milk), melanotrasferrin(present on melanoma cells) and ovotransferrin(present in egg white). TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis

IMMUNOGEN INFORMATION

Immunogen

transferrin

Synonyms

Beta 1 metal binding globulin, DKFZp781D0156, PRO1557, PRO2086, Serotransferrin, Siderophilin, TF, Transferrin

Observed MW

77 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:2000-1:20000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P02787

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