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FineTest

SKU:FNab09051

anti- TSP50 antibody

anti- TSP50 antibody

Regular price $310.00 USD
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size

anti- TSP50 antibody

Product Name

TSP50 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

TSP50(Testis-specific protease-like protein 50) is also named as PRSS50, CT20 and belongs to the peptidase S1 family. It can enhance the expression of NFKB target genes involved in cell proliferation, and promotes cell proliferation, at least partially, through activation of the NFKB signalling pathway(PMID:21385156). There are two protein bands of 37 kDa and 43 kDa to be detected in human testes that the the difference is most likely caused by posttranslational proteolytic cleavage(PMID:11782390). The full length protein has a signal peptide with 39 amino acids and two glycosylation sites.

IMMUNOGEN INFORMATION

Immunogen

testes-specific protease 50

Synonyms

Cancer/testis antigen 20, CT20, PRSS50, Serine protease 50, testes protease 50, TSP50

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

A0A140VJY3/Q9UI38

IMAGES

 

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab09051(TSP50antibody) at dilution of 1:50
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab09051(TSP50 antibody) at dilution of 1:300

 

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