anti- TWIST2 antibody

anti- TWIST2 antibody

Product Name

TWIST2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism(By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

IMMUNOGEN INFORMATION

Immunogen

twist homolog 2

Synonyms

BHLHa39, Dermis expressed protein 1, Dermo 1, DERMO1, twist homolog 2(Drosophila), Twist related protein 2, TWIST2

Observed MW

21 kDa, 65 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q8WVJ9

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