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Immunohistochemistry of paraffin-embedded human breast cancer using FNab09133(TXNRD1 antibody) at dilution of 1:100 -
IP Result of anti-TXNRD1 (IP:FNab09133, 3ug; Detection:FNab09133 1:500) with Jurkat cells lysate 1500ug. -
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09133(TXNRD1 antibody) at dilution of 1:500
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SKU:FNab09133
anti- TXNRD1 antibody
anti- TXNRD1 antibody
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anti- TXNRD1 antibody
Product Name
TXNRD1 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
IMMUNOGEN INFORMATION
Immunogen
thioredoxin reductase 1
Synonyms
GRIM 12, GRIM12, KDRF, thioredoxin reductase 1, Thioredoxin reductase TR1, TR, TR1, TRXR1, TXNR, TXNRD1
Observed MW
54 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IF, FC, IP
Recommended Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100; IP: 1:200-1:2000
UNIPROT INFORMATION
UniProt ID
IMAGES
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