anti- VAMP7/TI-VAMP antibody

anti- VAMP7/TI-VAMP antibody

Product Name

VAMP7/TI-VAMP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7.

IMMUNOGEN INFORMATION

Immunogen

vesicle-associated membrane protein 7

Synonyms

SYBL1, Synaptobrevin like protein 1, Tetanus insensitive VAMP, TI VAMP, TI-VAMP, VAMP 7, VAMP7

Observed MW

20 kDa, 50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200；IF: 1:10-1:100; IP: 1:500-1:5000

UNIPROT INFORMATION

UniProt ID

P51809

IMAGES