anti- VPS8 antibody

anti- VPS8 antibody

Product Name

VPS8 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).

IMMUNOGEN INFORMATION

Immunogen

vacuolar protein sorting 8 homolog

Synonyms

FLJ32099, KIAA0804, VPS8

Observed MW

151 kDa

APPLICATION

Tested Application

ELISA, WB, IF,IP

Recommended Dilution

WB: 1:500-1:5000；IP: 1:200-1:2000; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q8N3P4

IMAGES