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FineTest

SKU:FNab09488

anti- WDR24 antibody

anti- WDR24 antibody

Regular price $330.00 USD
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size

anti- WDR24 antibody

Product Name

WDR24 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).

IMMUNOGEN INFORMATION

Immunogen

WD repeat domain 24

Synonyms

C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24

Observed MW

102 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q96S15

IMAGES

Immunohistochemistry of paraffin-embedded human ovary using FNab09488(WDR24 antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09488(WDR24 antibody) at dilution of 1:500
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